Medical Products Supplies Companies

Raheen Business Park Raheen, V94 VH22 Limerick
Ireland
Telephone +353 61 300300
Fax +353 61 480456
ralla@arglobal.com

Pressure-Sensitive Adhesive Manufacturer

Product Categories

Product categories

01 Manufacturing of components
01.09 Other component manufacturing

Other component manufacturing

07 Microtechnology
07.07 Microfluidics

Microfluidics

ARx (Drug Delivery Systems)
ARx Buccal, Sublingual and Mucosal Thin Films

08 Raw materials, materials, adhesives
08.08 Adhesives

Adhesives

SoftWear Gentle Removal Adhesives
Long-Term Wear Adhesives
Weight-Bearing Adhesives
Hydrophilic Adhesives and Coatings
Dissolvable Films for Medical Applications
Electrically Conductive Adhesives and Films

08 Raw materials, materials, adhesives
08.09 Other raw materials, materials, adhesives

Other raw materials, materials, adhesives
Our products
Product category: Adhesives
SoftWear Gentle Removal Adhesives
SoftWear® skin adhesives remove gently to enhance patient comfort and minimize the risk of damage to skin upon removal. The family of SoftWear pressure-sensitive adhesives (PSAs) is available in non-silicone and silicone formulations from Adhesives Research.

SoftWear adhesives release cleanly from hair and skin with virtually painless removal to deliver secure, intimate skin contact for wound care and body-worn device applications. The sustained adhesion achieved with SoftWear adhesives allows for repositioning without compromise to dressing security.

Benefits of this technology:

Formulated for pediatric, geriatric and compromised skin
Silicone and non-silicone formulations available
Low-pain on removal (Wong Baker <2)
Tailorable wear times (up to 3 Days)
Breathable (MVTR of 1,000 g/m2/day on non-woven)
Retains adhesive properties at 25 kGy (Gamma)
Repositionable for wound monitoring
Residue-free removal
Low profile reduces edge lift
Biocompatible per ISO 10993
Customizable product constructions

Applications:

Wound care dressings
Wearable sensors and devices
Transdermal drug delivery

Product category: Adhesives
Long-Term Wear Adhesives
ARcare® skin-friendly, long-term wear (LTW) adhesive technologies are formulated to promote healing or deliver therapies in applications requiring wear times up to seven days. This adhesive is well-suited for extended wear times in dressings intended for difficult-to-adhere wound sites or skin-bonded devices.

Benefits of this technology:

Secure wear, minimal edge lift (7 days and beyond)
Minimal pain upon removal (Wong Baker <3)
Tailorable wear times
Limited adhesive & dressing creep
Residue-free removal
Breathable (MVTR of 1,000 g/m2/day on PU film)
Retains adhesive properties at 25 kGy (Gamma)
Biocompatible per ISO 10993

Applications:

Wound care dressing
Skin-bonded monitoring devices (wearable sensors)
Drug or therapeutic delivery systems (infusion pumps)
Transdermal patches

Product category: Adhesives
Weight-Bearing Adhesives
ARcare® weight-bearing adhesives secure skin-bonded devices, such as wearable sensors and therapy devices with moderate weight, for periods of time of a few hours, up to seven days.

Benefits of this technology:

Reliable bonds with comfortable removal
Tailorable wear times
Supports 75 gram device for 7 days+
Removes without compromising skin integrity
Good shear resistance for less movement
10X Standard Acrylics
Retains adhesive properties at 25 kGy (Gamma)
Biocompatible per ISO 10993

Applications:

Wearable sensors
Infusion pumps
Drug or therapeutic delivery systems

Product category: Adhesives
Hydrophilic Adhesives and Coatings
Adhesives Research’s ARflow® proprietary hydrophilic adhesive technologies reduce the surface tension of fluids (water, urine or blood), allowing for rapid flow from the inlet area to a remote reagent site within diagnostic and microfluidic devices. AR’s ARflow® hydrophilic surface technologies are available as pressure-sensitive adhesives (PSAs), heat-seals and coatings.

Benefits of this technology:

Compatible with sensitive chemistries
Demonstrates strong bonding to low-surface energy plastics
Tailorable hydrophilic properties to regulate capillary fill time
Readily customizable product construction including thickness, choice of substrate and release liner
Clean die-cuts improve manufacturing efficiencies and capillary performance

Applications:

Spacers
Lidding and covers

Product category: Adhesives
Dissolvable Films for Medical Applications
Adhesives Research’s dissolvable film technologies are polymer films that may contain reagents or other active materials designed to erode or dissolve at predetermined rates when in contact with a biological fluid or other liquid. This is an efficient medium for stabilizing sensitive reagents, delivering therapeutic agents or dispersing pigments. The dissolvable films’ dissolution rates are completely customizable to enable each pre-measured, preservative-free film strip to deliver a specified release over time.

Benefits of this technology:

Tailorable characteristics such as thickness, dissolution rate, texture and tensile strength
Provides concentrated doses of reagent or therapy within a homogenous film coating
Dry film format improves reagent/active ingredient stability
Allows for more efficient use of reagents/active ingredient when compared to other distribution techniques such as spraying
Provides separation of reagents/active ingredient components
Enables continuous web processing

Product category: Adhesives
Electrically Conductive Adhesives and Films
Adhesives Research (AR) offers homogeneous, electrically conductive pressure-sensitive adhesive (PSA) technology, which has proven success of increasing the functionality of electronic applications for more than 20 years. These PSAs can be used for transmitting current through layers of a device, forming electrical interconnections and bonding electrical components.

Benefits of this technology:

Homogenous conductive adhesive technology for stability & consistency
Enables smaller designs through thin, effective bonds
Reliable electrical contact without pressure
Combines excellent bond strength with stable conductivity, even under mechanical & environmental stress
Offers excellent & tailorable X, Y & Z conductivity
Bonds in ambient temperatures while providing stable performance in extreme temperature & humidity conditions
Enables electrical conductivity between or across adhesive bonds
Offers tailorable volume and surface resistance
Provides reliable bonds with strong cold drop performance and shock resistance

AR’s pressure-sensitive adhesives are used in the electronics field for:

Electrical interconnection and assembly
Foil-backed conductive PSAs for EMI/RFI shielding, electrical grounding and photovoltaic charge collection tapes
Static dissipation and control
Medical electronics

We also offer skin-friendly conductive adhesives and tapes for electrical interconnects, grounding and shielding in medical and pharmaceutical applications including:

Medical electronics
Medical devices
Wearable sensors
Transdermal/combination drug delivery devices

Product category: Microfluidics
ARx (Drug Delivery Systems)
As a leading industry expert of drug-loaded dissolvable film and patch delivery systems, ARx is an innovative development and manufacturing partner for novel drug products. ARx’s work expands dosage form possibilities for new or existing drug products by enhancing bioavailability and increasing patient compliance. The result is enriched patient well-being through robust drug delivery systems.

ARx focuses primarily on transdermal and transmucosal routes of administration to leverage our proven expertise in Quality by Design (QbD)-based controls, formulation, analytical testing, mixing, coating and drying. Our drug delivery systems and expertise include:
oral, buccal, sublingual and mucosal thin films, and transdermal patches.

As an extension of our customers’ project teams, ARx builds a collaborative development plan based upon the needs of the filing strategy, QbD principles and critical milestones. Project experience spans a range of therapies in support of FDA ANDA’s, 505(b)(1) and 505(b)(2) NDA’s, in addition to support for filings with global agencies around the world.

Product category: Microfluidics
ARx Buccal, Sublingual and Mucosal Thin Films
Buccal, sublingual and mucosal thin films from ARx, LLC provide added bioavailability benefits and fast API absorption compared to traditional dosage forms.

ARx custom formulates and manufactures drug-loaded mucosal film systems, designed to bond to challenging mucosal tissues for specified periods of time, while proving comfortable for the patient. The systems may be single or multi layer and formulated for removal upon treatment, or to completely erode at a pre-determined time. Multi-layer systems provide an added benefit in insuring API penetration through mucosal tissue before the entire system is dissolved.

Dissolvable films integrate most available forms of active pharmaceutical ingredients (APIs), including micronized, granulated, salt and free-base forms. Both soluble and insoluble drugs have been successfully compounded into solutions and suspensions which are further processed into a dissolvable film. Active concentrations of larger particle sized compounds are possible up to 50% of the final unit mass; the intended dose is achieved by determining and precisely controlling the size and thickness of the final film.

Benefits of ARx buccal, sublingual and mucosal thin film technologies:

Formulation Flexibility:

Tailorable film characteristics including dissolution rates, adhesion, film thickness, material composition, taste-masking and API absorption rates
Dissolution may be triggered for a specific biological fluid, pH or other condition
Multi-layered product constructions available for optimum bio-availability and stability
A variety of excipient options for API compatibility and stability
Multi-layered product constructions available for stability and efficacy
Novel dosage format for product line extension
Delivery of stable drug compounds and GRAS ingredients through excipient selection and product design

Patient Convenience:

Eliminates the need to swallow medication
Discrete, easy to transport and administer
Comfortable and discrete during dosing
Pleasant taste and mouth feel
Improved market success through enhanced compliance

Drug Delivery Benefits:

Systemic drug delivery through mucosal absorption
Bypass first pass metabolism effect
Bypass enzymatic degradation
Less API needed to achieve therapeutic response for cost savings and less potential for abuse
Rapid onset and drug absorption
Controlled pH for optimized drug delivery

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About Us

Company details
Adhesives Research, Inc. (AR) is a leading global independent developer and manufacturer of pressure-sensitive adhesives (PSAs), polymers, tapes, films, coatings, laminates, release liners and drug delivery systems.

We are committed to being the most effective company in our field by:

Partnering with our customers
Developing and manufacturing the specialized products our customers seek for improving their product.

Established in 1961, AR’s humble beginnings originated in a converted garage to develop and supply specialty adhesive-coated materials and processing equipment to meet the evolving needs of the graphics arts label market.

Through several moves and expansions, AR grew steadily, developing new capabilities and technologies that enabled the company to address the unmet needs of new markets. Rapid growth led to facility expansions to include the U.S., South America (1980), Europe (1999) and Asia (2000). With headquarters in Glen Rock, PA and Limerick, Ireland, today the company’s facilities span over 250 acres, cover over 300,000+ square feet of development and manufacturing space and employ approximately 300 associates.

Adhesives Research, Inc. is organized into two unique businesses:

Adhesives Research supplies high-performance specialty films, PSAs, tapes, coatings, films, laminates and components to the medical, pharmaceutical, electronics, industrial, and splicing markets
ARx, LLC, a wholly-owned subsidiary, develops and manufactures client-specific transdermal and thin film drug delivery systems with pharmaceutical and biotech partners.

During the past 50+ years, AR has emerged as a leader in our field through the continuous development of core technologies and capabilities. Today we remain an independent company, committed to working with customers as our partners in the development of application-specific products that fill their unmet material needs.

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