microLIQUID S.L.

C/ Goiru, 1 Edificio B / Planta 2, 20500 Mondragón
Spain
Telephone +34 943 846837
info@microliquid.com
http://www.microliquid.com

Product Categories

Product categories

02 Manufacturing of finished products
02.15 In-vitro diagnostics (IVD)

In-vitro diagnostics (IVD)

02 Manufacturing of finished products
02.16 Laboratory technologies
02.16.01 Lab-on-a-chip

Lab-on-a-chip

02 Manufacturing of finished products
02.17 Biomedical products

Biomedical products

07 Microtechnology
07.07 Microfluidics

Microfluidics

Our products

Product category: Microfluidics
Microfluidic Custom Design and Mass-Manufacturing
We are experts in the development and manufacture of microfluidic products.
microLIQUID is a one-stop provider of end-to-end Bioscience solutions, spanning the whole microfluidic value chain from cartridges to equipment. Our microfluidic OEM cartridge technologies, as well as the microfluidic ODM ones, fit the demand for improving the efficiency of techniques applied in the manufacturing of microfluidic products, such as IVD devices and microfluidic chips.

Starting with potential microfluidic design, development and proof of concept, we work together with our customers on projects of potentially fully-certified microfluidic IVD development and manufacturing. This is possible as we have Bioscience, Engineering and New Product Introduction expertise all under one roof.

One of our key strengths is the ability to provide novel processing solutions where conventional microfluidics manufacturing processes are no longer valid. The challenges that we regularly address entail the inclusion of micro-sized features as well as the design and manufacturing of several types of micro mold technologies (Silicon, PDMS, SU-8 and steel), the combination of micro and macro features, combinations of process steps, challenging assembly steps, stringent QC requirements and packaging of the final product. Our manufacturing team deliver small and large volumes of products to customers around the world. microLIQUID offers full solutions for microfluidic design and manufacturing of macro-, micro-, nano-structured and multi-layer polymer devices, in some cases also with silicon and glass material in hybrid solutions for the market. microLIQUID provides microfluidic cartridge development for customers´ proprietary platforms, whilst also offering a full solution from microfluidics through precision flow control equipment.

Since the creation of our company 10 years ago, we have built up experience working on thousands of Research and Development projects, as well as large-scale ones with international vocation. Being able to communicate in English, French and Spanish, microLIQUID has developed a unique combination of skills including microfluidic design, nano- and microfabrication, polymer sciences and automated assembly, all of which have been implemented in our microfluidics mass-production facilities.

Our technology ranges from state-of-the art MEMS and Microfluidic technologies to micro-injection molding capabilities. microLIQUID integrates all these manufacturing process techniques:

Photolithography technologies (class 10-100)
Thin film processing: Sputtering, Oxidation furnaces etc.
Plasma etching: RIE and DRIE
Microreplication: Hot embossing, casting, micro milling
Micro Injection molding
Surface functionalization
Automated Reagent deposition/integration
Bonding technologies (solvent, wire, ultrasonic, anodic, fusion and adhesive bonding)
High throughput Lamination equipment (adhesive and thermal)
Assembly and interfacing

Product category: Biomedical products, Microfluidics
MICROFLUIDIC-IMMUNOASSAY
The high sensitivity and specificity of immunoassays make them a powerful tool in molecular diagnostics. microLIQUID, has proven that microfluidics is making a change in the field of diagnostics.

The current immunoassay ‘gold standard’ ELISA, while proven to be highly robust and reliable, suffers from large sample requirements, long diffusion times, and hence, long incubation times moreover, it requires a specific enzyme-fluorophore complex that does not interfere with the reaction.

In recent years, microLIQUID has focused on combining the classic ELISA approach with microfluidic technologies. Such devices enable quantitative immunoassay results by integrating sensitive optical or electrochemical detection methods. The main advantages of a microfluidic immunoassay compared to conventional approaches are:

Increase throughout and reproducibility, with automatic microfluidic immunoassay system.
Lower consumption of samples and reagents.
Speed up the antibody-antigen binding reactions.

Summarizing, the combination of microfluidics and immunoassay technologies can detect biomarkers with faster assay time, reduced volumes of reagents, lower power requirements, and higher levels of integration and automation compared to traditional approaches.

Product category: In-vitro diagnostics (IVD), Lab-on-a-chip, Biomedical products
IVD Automation & Instrumentation
Starting with design and proof of concept, we work with our company partners from development to mass-production of potentially fully-certified IVD or Pharma solutions. This is possible thanks to the fact that we have built up our expertise in Bioscience and Automated Instrumentation, which enables us to offer the whole value chain with both quality and speed in our services.

We are experts in the development and manufacture of immunoassays and molecular diagnostics platforms, such as microarrays, a wide range of biosensors, PCR/RT-PCR, sample preparation applications, liquid biopsy, NGS etc. Thanks to the extensive background and ample qualifications of our engineers and scientists, we can guide you in the process of Bio-translation from the bench to the market. Our experience is essential to establish the process of development of new technologies and the successful translation to automated cartridge solutions.

We work closely with our clients and we combine our microfluidic engineering and instrument expertise to accomplish the goals in every step of the product development process and production. We add value to our customers ́ business by leveraging our core strengths (smart consumables, microfluidic cartridges, flow and thermal control and several assays and biosensing integration strategies) to deliver highest quality and outstanding service and will ensure commercial success in several fields:

Instruments for Point of Care IVD.
Lab-on-a-chip solutions for sample preparation and diagnostics.
Drug delivery.
Customized instrumentation.

Product category: Biomedical products, Microfluidics
MOLECULAR DIAGNOSTICS
Molecular diagnostics have improved the diagnosis and treatment of millions of patients worldwide, allowing clinicians to diagnose patients earlier and provide better ongoing therapies.

At microLIQUID, we develop fully automated sample preparation and molecular diagnostic systems based on microfluidics.

Non-microfluidic diagnostic instruments usually require large quantities of costly reagents, long analysis time, established lab infrastructure, and trained professionals to operate. This limits their practicality for large-scale screening applications in developed countries, and for primary care in developing countries. There is a strong demand for robust, cost-effective and simple-to-operate molecular diagnostic instruments.

Microfluidic systems have many advantages, such as short analysis time, reduction in production costs, and low sample/reagent consumption.

However, there are also important differences among microfluidic devices. Most current microfluidic diagnostic devices are designed to target a single disease, such as a given cancer or a particular strain of a pathogen. The future of molecular diagnostics lies in highly multiplexed microfluidic devices that can screen for potentially hundreds of diseases simultaneously.

microLIQUID is committed to the development of these kinds of diagnostic systems and has the experience and expertise to develop and manufacture fully automated sample preparation and molecular diagnostic systems.

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About Us

Company details
Having built up experience working on thousands of Research and Development as well as large-scale projects, microLIQUID has developed a unique combination of skills including microfluidic design, nano- and microfabrication, polymer sciences and automated assembly, all of which have been set to work in our mass-production facilities.

microLIQUID also develops and manufactures fully automated analyzer systems and drug delivery equipment focused on diagnostics and pharmaceutical markets. With capabilities spanning the entire value chain, microLIQUID has become a one-stop provider of end-to-end solutions.

Our engineers and scientists have an extensive background and ample qualifications in the development and manufacture of immunoassays and molecular diagnostics platforms, among others.

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